What is one concerning side effect of high-dose Trazodone during perinatal use?

Impaired nighttime caregiving is a significant concern when using high-dose Trazodone during the perinatal period. Trazodone, an antidepressant primarily used for its sedative effects, can cause sedation that impairs a person's ability to effectively care for a newborn during nighttime hours. Adequate alertness and responsiveness are crucial for the safety and well-being of the infant, particularly during feedings, diaper changes, and other caregiving tasks that may occur throughout the night.

In the context of perinatal mental health, it's essential to consider the balance between managing maternal mental health and ensuring the safety of both mother and baby during this vulnerable time. This concern highlights the importance of careful monitoring and possible adjustment of medication dosages and timings to minimize risks associated with impaired caregiving. The other options do not reflect the risks associated with high doses of Trazodone; options relating to increased alertness, decreased sedation, or improved mood stability do not align with the medication's profile and its sedative properties, especially at higher doses.